Bisphenol F (BPF)
Bisphenol F (BPF) is a common substitute for BPA, but has recently been scrutinized for its potential toxicity. BPF can often be found in adhesives, varnishes, water pipes, and other epoxy resin products.
Bisphenol F (BPF), a common alternative to bisphenol A (BPA), has sparked increasing concerns due to its potential metabolic toxicity. Bisphenol F consists of isomeric and oligomeric products. It is used in the production of epoxy resins and coatings for various applications, including lacquers, varnishes, liners, adhesives, plastics, water pipes, dental sealants, and food packaging.
Exposure to BPF in occupational settings can happen through inhaling dust and skin contact with the compound at sites where it is manufactured or utilized. Data suggest that the general public encounters BPF by inhaling household dust, consuming soda, and potentially through skin contact with consumer products that include resins and coatings made with bisphenol F.
BPF primarily induced necrotic changes in human peripheral blood mononuclear cells and exhibited anti-androgenic effects in human cell lines. Recent research indicates that exposure to BPF is linked to lipid accumulation and changes resembling non-alcoholic fatty liver disease (NAFLD).
Sources:
https://doi.org/10.1016/j.ecoenv.2025.119000
https://pubchem.ncbi.nlm.nih.gov/compound/12111#section=Interactions
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